NEJIRE/DCBP-MEDIATED HISTONE H3 ACETYLATION DURING SPERMATOGENESIS IS ESSENTIAL FOR MALE FERTILITY IN DROSOPHILA MELANOGASTER.

Nejire/dCBP-mediated histone H3 acetylation during spermatogenesis is essential for male fertility in Drosophila melanogaster.

Spermatogenesis in many species including Drosophila melanogaster is accompanied by major reorganisation of chromatin in post-meiotic stages, involving a nearly genome-wide displacement of histones by protamines, Mst77F and Protamine-like 99C.A proposed prerequisite for the histone-to-protamine transition is massive histone H4 hyper-acetylation pri

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